美貌的小镇教师斯黛拉(伊丽莎白·班克斯 Elizabeth Banks 饰)在母亲过世后得到当地富豪格兰特(迈克尔·鲁克 Michael Rooker 饰)的多方照顾,嫁给他后尽管诸多不满,却依然努力成为一个合格的妻子。有次二人吵架后格兰特愤而出走,被神秘的外星生物侵入体内,第二日清早回家性情大变。于此同时,小镇的宠物狗开始神秘失踪,曾与格兰特在酒吧一同饮酒的女孩布兰达(布兰达·詹姆斯 Brenda James 饰)也不见了踪影。在发现了格兰特开始腐烂变异的脸后,惊恐的斯黛拉求助于小镇警长比尔和众警员(内森·菲利安 Nathan Fillion 饰),但众人均被吓坏,格兰特借此逃脱。众人决定在附近农场猎捕格兰特,却没想到这竟导致了怪异生物的大蔓延,整个小镇都处于极度危险之中。
本片被提名2007年美国科幻、幻想及恐怖电影协会最佳恐怖电影奖,并获最佳化妆土星奖。
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