The plot consists of the interwoven stories of three couples who are forced to make life-altering decisions in the face of a disastrous war. Inspired and sometimes blinded by their love, Len (Josh Hartnett), Mia (Rosario Dawson), Andy (Frank Langella), Esther (Gena Rowlands), Anna (Teresa Palmer) and Erik (Penn Badgley) are as flawed and beautiful as any of the billions who are facing this human-made biological disaster.